Functional assays to determine the significance of two common <it>XPC </it>3'UTR variants found in bladder cancer patients

<p>Abstract</p> <p>Background</p> <p><it>XPC </it>is involved in the nucleotide excision repair of DNA damaged by carcinogens known to cause bladder cancer. Individuals homozygous for the variant allele of <it>XPC </it>c.1496C > T (p.Ala499Val...

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Bibliographic Details
Main Authors: Bishop D, Hall Janet, Bentley Johanne, Vaslin Laurence, Elliott Faye, Scott Gina B, Qiao Boling, Knowles Margaret A, Kiltie Anne E
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/12/84