Hypo-Expression of Flice-Inhibitory Protein and Activation of the Caspase-8 Apoptotic Pathways in the Death-Inducing Signaling Complex Due to Ischemia Induced by the Compression of the Asphyxiogenic Tool on the Skin in Hanging Cases

The FLICE-inhibitory protein (c-FLIPL) (55 kDa) is expressed in numerous tissues and most abundantly in the kidney, skeletal muscles and heart. The c-FLIPL has a region of homology with caspase-8 at the carboxy-terminal end which allows the molecule to assume a tertiary structure similar to that of...

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Bibliographic Details
Main Authors: Aniello Maiese, Alessandra De Matteis, Giorgio Bolino, Emanuela Turillazzi, Paola Frati, Vittorio Fineschi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/10/11/938