Propensity Score-Based Approaches in High Dimension for Pharmacovigilance Signal Detection: an Empirical Comparison on the French Spontaneous Reporting Database

Propensity Score-Based Approaches in High Dimension for Pharmacovigilance Signal Detection: an Empirical Comparison on the French Spontaneous Reporting Database

Classical methods used for signal detection in pharmacovigilance rely on disproportionality analysis of counts aggregating spontaneous reports of a given adverse drug reaction. In recent years, alternative methods have been proposed to analyze individual spontaneous reports such as penalized multipl...

Full description

Bibliographic Details
Main Authors: Émeline Courtois, Antoine Pariente, Francesco Salvo, Étienne Volatier, Pascale Tubert-Bitter, Ismaïl Ahmed
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
pharmacovigilance
signal detection
propensity score in high dimension
spontaneous reports
penalized multiple regression
FDR
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01010/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01010/full

Similar Items