Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer.

Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer.

Buruli ulcer (BU) is a severe necrotizing human skin disease caused by Mycobacterium ulcerans. Clinically, presentation is a sum of these diverse pathogenic hits subjected to critical immune-regulatory mechanisms. Among them, autophagy has been demonstrated as a cellular process of critical importan...

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Main Authors: Carlos Capela, Ange Dodji Dossou, Rita Silva-Gomes, Ghislain Emmanuel Sopoh, Michel Makoutode, João Filipe Menino, Alexandra Gabriel Fraga, Cristina Cunha, Agostinho Carvalho, Fernando Rodrigues, Jorge Pedrosa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4851401?pdf=render

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http://europepmc.org/articles/PMC4851401?pdf=render

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