Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission.

Globally re-emerging dengue viruses are transmitted from human-to-human by Aedes mosquitoes. While viral determinants of human pathogenicity have been defined, there is a lack of knowledge of how dengue viruses influence mosquito transmission. Identification of viral determinants of transmission can...

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Bibliographic Details
Main Authors: Julien Pompon, Menchie Manuel, Geok Kee Ng, Benjamin Wong, Chao Shan, Gayathri Manokaran, Ruben Soto-Acosta, Shelton S Bradrick, Eng Eong Ooi, Dorothée Missé, Pei-Yong Shi, Mariano A Garcia-Blanco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5555716?pdf=render