β-Apopicropodophyllin functions as a radiosensitizer targeting ER stress in non-small cell lung cancer

β-Apopicropodophyllin functions as a radiosensitizer targeting ER stress in non-small cell lung cancer

Aims: In this study, we examined whether β-apopicropodophyllin (APP) could act as a radiosensitizer in non-small cell lung cancer (NSCLC) cells. Main methods: The in vitro radiosensitizing activity of APP was demonstrated with clonogenic assay, immunoblotting, Annexin V-Propidium iodide (PI) assay,...

Full description

Bibliographic Details
Main Authors: Ju Yeon Kim, Jeong Hyun Cho, Eun Mi Kim, Hyun-Jin Shin, Sang-Gu Hwang, Jie-Young Song, Hong-Duck Um, Jong Kuk Park
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
β-Apopicropodophylli
Radiosensitizer
ER stress
ROS
Apoptosis
Non-small cell lung cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219305256

Internet

http://www.sciencedirect.com/science/article/pii/S0753332219305256

Similar Items