The interaction of Epstein-Barr virus encoded transcription factor EBNA2 with multiple sclerosis risk loci is dependent on the risk genotype

Background: Epstein-Barr virus (EBV) infection may be necessary for the development of Multiple sclerosis (MS). Earlier we had identified six MS risk loci that are co-located with binding sites for the EBV transcription factor Epstein-Barr Nuclear Antigen 2 (EBNA2) in EBV-infected B cells (lymphobla...

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Bibliographic Details
Main Authors: Jeremy Thomas Keane, Ali Afrasiabi, Stephen Donald Schibeci, Sanjay Swaminathan, Grant Peter Parnell, David Richmond Booth
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:EBioMedicine
Subjects:
MS
EBV
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003650