TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages

TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages

Regulation of proinflammatory cytokine expression is critical in the face of single-stranded RNA (ssRNA) virus infections. Many viruses, including coronavirus and influenza virus, wreak havoc on the control of cytokine expression, leading to the formation of detrimental cytokine storms. Understandin...

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Bibliographic Details
Main Authors: Natalya Odoardi, Olena Kourko, Carlene Petes, Sameh Basta, Katrina Gee
Format: Article
Language:English
Published: Karger Publishers 2021-05-01
Series:Journal of Innate Immunity
Subjects:
interleukin-27
toll-like receptor 7
toll-like receptor 8
toll-like receptor
interferon
monocytes
macrophages
inflammation
Online Access:https://www.karger.com/Article/FullText/515738

Internet

https://www.karger.com/Article/FullText/515738

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