Transcriptomic analysis of the mouse retina after acute and chronic normobaric and hypobaric hypoxia

Abstract Oxygen delivery to the retinal pigment epithelium and the outer retina is essential for metabolism, function, and survival of photoreceptors. Chronically reduced oxygen supply leads to retinal pathologies in patients and causes age-dependent retinal degeneration in mice. Hypoxia can result...

Full description

Bibliographic Details
Main Authors: L. J. A. Ebner, M. Samardzija, F. Storti, V. Todorova, D. Karademir, J. Behr, F. Simpson, M. Thiersch, C. Grimm
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96150-9