The Potential Pathogenic Contributions of Endothelial Barrier and Arterial Contractile Dysfunction to Shock Due to B. anthracis Lethal and Edema Toxins

Shock with B. anthracis infection is particularly resistant to conventional cardiovascular support and its mortality rate appears higher than with more common bacterial pathogens. As opposed to many bacteria that lack exotoxins directly depressing hemodynamic function, lethal and edema toxin (LT and...

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Bibliographic Details
Main Authors: Dante A. Suffredini, Xizhong Cui, Wanying Xu, Yan Li, Peter Q. Eichacker
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/9/12/394