A comparative antibody analysis of Pannexin1 expression in four rat brain regions reveals varying subcellular localizations

A comparative antibody analysis of Pannexin1 expression in four rat brain regions reveals varying subcellular localizations

Pannexin1 (Panx1) channels release cytosolic ATP in response to signaling pathways. Panx1 is highly expressed in the central nervous system. We used four antibodies with different Panx1 anti-peptide epitopes to analyze four regions of rat brain. These antibodies labeled the same bands in Western blo...

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Bibliographic Details
Main Authors: Angela C Cone, Cinzia eAmbrosi, Eliana eScemes, Maryann E Martone, Gina eSosinsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Pharmacology
Subjects:
knockout mouse
connexin
purinergic receptors
paracrine signaling
pannexin channels
ATP signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00006/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00006/full

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