Early IGF-1 Gene Therapy Prevented Oxidative Stress and Cognitive Deficits Induced by Traumatic Brain Injury

Early IGF-1 Gene Therapy Prevented Oxidative Stress and Cognitive Deficits Induced by Traumatic Brain Injury

Traumatic Brain Injury (TBI) remains a leading cause of morbidity and mortality in adults under 40 years old. Once primary injury occurs after TBI, neuroinflammation and oxidative stress (OS) are triggered, contributing to the development of many TBI-induced neurological deficits, and reducing the p...

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Bibliographic Details
Main Authors: Agustín. J. Montivero, Marisa. S. Ghersi, M. Jazmín Silvero C, Emilce Artur de la Villarmois, Johanna Catalan-Figueroa, Macarena Herrera, María Cecilia Becerra, Claudia. B. Hereñú, Mariela. F. Pérez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
traumatic brain injury
neuroinflammation
secondary injury
cognitive deficits
IGF-1 gene therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.672392/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.672392/full

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