Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study.

BACKGROUND: CagA cellular interaction via activation of the ERK signaling pathway may be a starting point in the development of gastric cancer. This study aimed to evaluate whether genes involved in ERK downstream signaling pathways activated by CagA are susceptible genetic markers for gastric cance...

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Main Authors: Jae Jeong Yang, Lisa Y Cho, Seung Hyun Ma, Kwang-Pil Ko, Aesun Shin, Bo Youl Choi, Dong Soo Han, Kyu Sang Song, Yong Sung Kim, Soung-Hoon Chang, Hai-Rim Shin, Daehee Kang, Keun-Young Yoo, Sue K Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3116873?pdf=render