HPV16 E6/E7 upregulates HIF-2α and VEGF by inhibiting LKB1 in lung cancer cells
Long-term persistent infection of HPV16 E6/E7 is frequently associated with lung cancers, especially in non-smokers and in Asians. However, molecular mechanisms of HPV16 E6/E7 induction of lung cancer are not fully understood. Using bi-directional genetic manipulation and four well-established lung...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-07-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317717137 |