High Frequency of CD8 Positive Lymphocyte Infiltration Correlates with Lack of Lymph Node Involvement in Early Rectal Cancer

High Frequency of CD8 Positive Lymphocyte Infiltration Correlates with Lack of Lymph Node Involvement in Early Rectal Cancer

Aims. A trend towards local excision of early rectal cancers has prompted us to investigate if immunoprofiling might help in predicting lymph node involvement in this subgroup. Methods. A tissue microarray of 126 biopsies of early rectal cancer (T1 and T2) was stained for several immunomarkers of th...

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Main Authors: Silvio Däster, Serenella Eppenberger-Castori, Christian Hirt, Inti Zlobec, Tarik Delko, Christian A. Nebiker, Savas D. Soysal, Francesca Amicarella, Giandomenica Iezzi, Giuseppe Sconocchia, Michael Heberer, Alessandro Lugli, Giulio C. Spagnoli, Christoph Kettelhack, Luigi Terracciano, Daniel Oertli, Urs von Holzen, Luigi Tornillo, Raoul A. Droeser
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2014/792183

Internet

http://dx.doi.org/10.1155/2014/792183

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