Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition
Recent studies on tauopathy animal models suggest that the concomitant expression of the endogenous murine tau delays the pathological accumulation of human tau, and interferes with the disease progression. To elucidate the role of endogenous murine tau in a model with both plaques and tangles, we d...
Main Authors: | David Baglietto-Vargas, Masashi Kitazawa, Elaine J. Le, Tatiana Estrada-Hernandez, Carlos J. Rodriguez-Ortiz, Rodrigo Medeiros, Kim N. Green, Frank M. LaFerla |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-02-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996113002945 |
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