Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway

Abstract Sproutys are negative regulators of the Ras/Raf/MAPK signaling pathway and involved in regulation of organogenesis, differentiation, cell migration and proliferation. Although the function of Sproutys have been extensively studied during embryonic development, their role and mode of action...

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Bibliographic Details
Main Authors: Jian Sun, Jaeho Yoon, Moonsup Lee, Yoo-Seok Hwang, Ira O. Daar
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-70670-2