Wnt-dependent osteogenic commitment of bone marrow stromal cells using a novel GSK3β inhibitor

Bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) can differentiate into multiple lineages including osteogenic and adipogenic cells. Wnt signalling has been implicated in controlling BMSC fate, but the mechanisms are unclear and apparently conflicting data...

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Bibliographic Details
Main Authors: David A. Cook, Simon W. Fellgett, Mary E. Pownall, Patrick J. O'Shea, Paul G. Genever
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S187350611300144X