Novel photosensitizers trigger rapid death of malignant human cells and rodent tumor transplants via lipid photodamage and membrane permeabilization.

Novel photosensitizers trigger rapid death of malignant human cells and rodent tumor transplants via lipid photodamage and membrane permeabilization.

BACKGROUND: Apoptotic cascades may frequently be impaired in tumor cells; therefore, the approaches to circumvent these obstacles emerge as important therapeutic modalities. METHODOLOGY/PRINCIPAL FINDINGS: Our novel derivatives of chlorin e(6), that is, its amide (compound 2) and boronated amide (co...

Full description

Bibliographic Details
Main Authors: Mikhail M Moisenovich, Valentina A Ol'shevskaya, Tatyana I Rokitskaya, Alla A Ramonova, Roza G Nikitina, Arina N Savchenko, Victor V Tatarskiy, Mikhail A Kaplan, Valery N Kalinin, Elena A Kotova, Oleg V Uvarov, Igor I Agapov, Yuri N Antonenko, Alexander A Shtil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2939899?pdf=render

Internet

http://europepmc.org/articles/PMC2939899?pdf=render

Similar Items