Mapping genetic variants associated with beta-adrenergic responses in inbred mice.

β-blockers and β-agonists are primarily used to treat cardiovascular diseases. Inter-individual variability in response to both drug classes is well recognized, yet the identity and relative contribution of the genetic players involved are poorly understood. This work is the first genome-wide associ...

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Bibliographic Details
Main Authors: Micha Hersch, Bastian Peter, Hyun Min Kang, Fanny Schüpfer, Hugues Abriel, Thierry Pedrazzini, Eleazar Eskin, Jacques S Beckmann, Sven Bergmann, Fabienne Maurer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409184?pdf=render