Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

Nucleic acids, including DNA, microRNA (miRNA), small interfering RNA (siRNA), and antisense oligonucleotide (ASO), are powerful gene regulators, which have been demonstrated as promising drug candidates for therapeutic treatments. Nevertheless, poor cellular membrane permeability and serum stabilit...

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Bibliographic Details
Main Authors: Wenzhang Cha, Rengen Fan, Yufeng Miao, Yong Zhou, Chenglin Qin, Xiangxiang Shan, Xinqiang Wan, Jinbo Li
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
mesoporous silica nanoparticles
nucleic acids
drug delivery
therapeutics
Online Access:http://www.mdpi.com/1420-3049/22/5/782

Internet

http://www.mdpi.com/1420-3049/22/5/782

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