Cdh4 Down-Regulation Impairs in Vivo Infiltration and Malignancy in Patients Derived Glioblastoma Cells

Cdh4 Down-Regulation Impairs in Vivo Infiltration and Malignancy in Patients Derived Glioblastoma Cells

The high invasive phenotype of glioblastoma is one of the main causes of therapy inefficacy and tumor relapse. Cell adhesion molecules of the cadherin family are involved in cell migration and are known as master regulators of epithelial tumor invasiveness, but their role in glioblastoma is less und...

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Bibliographic Details
Main Authors: Davide Ceresa, Francesco Alessandrini, Lorenzo Bosio, Daniela Marubbi, Daniele Reverberi, Paolo Malatesta, Irene Appolloni
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
brain tumor
contact inhibition
R-cadherin
proliferation
migration
adherent junctions
cell polarity
Online Access:https://www.mdpi.com/1422-0067/20/16/4028

Internet

https://www.mdpi.com/1422-0067/20/16/4028

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