Evolution of Tumor Metabolism might Reflect Carcinogenesis as a Reverse Evolution process (Dismantling of Multicellularity)

Evolution of Tumor Metabolism might Reflect Carcinogenesis as a Reverse Evolution process (Dismantling of Multicellularity)

Carcinogenesis occurs through a series of steps from normal into benign and finally malignant phenotype. This cancer evolutionary trajectory has been accompanied by similar metabolic transformation from normal metabolism into Pasteur and/or Crabtree-Effects into Warburg-Effect and finally Cannibalis...

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Bibliographic Details
Main Authors: Adil H.H. Bashir, Gamal O. Elhassan, Abdel Khalig Muddathir, Mohammed E.A. Shayoub, Khalid O. Alfarouk
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Cancers
Subjects:
Warburg-effect
Crabtree-effect
Pasteur-effect
lactate symbiosis
cannibalism
reverse evolution
convergent evolution
Online Access:http://www.mdpi.com/2072-6694/3/3/3002/

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http://www.mdpi.com/2072-6694/3/3/3002/

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