Development of two distinct dendritic-like APCs in the context of splenic stroma
Murine splenic stroma has been found to provide an in vitro niche for hematopoiesis of dendritic-like APCs (APC). Two distinct cell types have been characterised. The novel ‘L-DC’ subset, has cross presenting capacity leading to activation of CD8+ T cells, but do not activate CD4+ T cells consistent...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-03-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00073/full |