Vaccination with L. infantum chagasi nucleosomal histones confers protection against new world cutaneous leishmaniasis caused by Leishmania braziliensis.

Vaccination with L. infantum chagasi nucleosomal histones confers protection against new world cutaneous leishmaniasis caused by Leishmania braziliensis.

<h4>Background</h4>Nucleosomal histones are intracellular proteins that are highly conserved among Leishmania species. After parasite destruction or spontaneous lysis, exposure to these proteins elicits a strong host immune response. In the present study, we analyzed the protective capab...

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Bibliographic Details
Main Authors: Marcia W Carneiro, Diego M Santos, Kiyoshi F Fukutani, Jorge Clarencio, Jose Carlos Miranda, Claudia Brodskyn, Aldina Barral, Manoel Barral-Netto, Manuel Soto, Camila I de Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284976/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284976/?tool=EBI

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