Effects of new generation triptans – frovatriptan and almotriptan – on hemodynamic parameters in intact male and female rats

The introduction of the second generation triptans in clinical and experimental practice was a major progress in the pharmacotherapy of migraine. Frovatriptan is a second generation triptan with strong 5-HT1B/1D serotonergic agonism and low 5-HT1A/7 receptor affinity, while almotriptan possesses not...

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Bibliographic Details
Main Authors: Saracheva Kremena, Hrischev Petar, Vasileva Liliya, Topolov Mariyan, Nikolova Julia, Getova Damianka
Format: Article
Language:English
Published: Sciendo 2020-06-01
Series:Acta Pharmaceutica
Subjects:
rat
Online Access:https://doi.org/10.2478/acph-2020-0005