Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans

Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans

The oncogenic Ras/MAPK pathway is evolutionarily conserved across metazoans. Yet, almost all our knowledge on this pathway comes from studies using single genetic backgrounds, whereas mutational effects can be highly background dependent. Therefore, we lack insight in the interplay between genetic b...

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Bibliographic Details
Main Authors: Mark G. Sterken, Linda van Bemmelen van der Plaat, Joost A. G. Riksen, Miriam Rodriguez, Tobias Schmid, Alex Hajnal, Jan E. Kammenga, Basten L. Snoek
Format: Article
Language:English
Published: Oxford University Press 2017-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Caenorhabditis elegans
RAS/MAPK
eQTL
genetic background
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.1120

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.1120

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