Trehalose Restrains the Fibril Load towards α-Lactalbumin Aggregation and Halts Fibrillation in a Concentration-Dependent Manner

Trehalose Restrains the Fibril Load towards α-Lactalbumin Aggregation and Halts Fibrillation in a Concentration-Dependent Manner

Protein aggregation and misfolding are some of the most challenging obstacles, customarily studied for their association with amyloid pathologies. The mechanism of amyloid fibrillation development is a dynamic phenomenon involving various factors such as the intrinsic properties of protein and the p...

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Bibliographic Details
Main Authors: Sania Bashir, Ishfaq Ahmad Ahanger, Anas Shamsi, Mohamed F. Alajmi, Afzal Hussain, Hani Choudhry, Faizan Ahmad, Md. Imtaiyaz Hassan, Asimul Islam
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomolecules
Subjects:
protein aggregation
trehalose
spectroscopy
transmission electron microscopy
molecular docking
Online Access:https://www.mdpi.com/2218-273X/11/3/414

Internet

https://www.mdpi.com/2218-273X/11/3/414

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