Transcriptomic profiles of aging in naïve and memory CD4+ cells from mice

Transcriptomic profiles of aging in naïve and memory CD4+ cells from mice

Abstract Background CD4+ T cells can be broadly divided into naïve and memory subsets, each of which are differentially impaired by the aging process. It is unclear if and how these differences are reflected at the transcriptomic level. We performed microarray profiling on RNA derived from naïve (CD...

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Bibliographic Details
Main Authors: Jackson Taylor, Lindsay Reynolds, Li Hou, Kurt Lohman, Wei Cui, Stephen Kritchevsky, Charles McCall, Yongmei Liu
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Immunity & Ageing
Subjects:
Aging
T cells
CD4+
Transcriptomic
NFKB
Enhancer
Online Access:http://link.springer.com/article/10.1186/s12979-017-0092-5

Internet

http://link.springer.com/article/10.1186/s12979-017-0092-5

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