The X chromosome and sex-specific effects in infectious disease susceptibility

Abstract The X chromosome and X-linked variants have largely been ignored in genome-wide and candidate association studies of infectious diseases due to the complexity of statistical analysis of the X chromosome. This exclusion is significant, since the X chromosome contains a high density of immune...

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Bibliographic Details
Main Authors: Haiko Schurz, Muneeb Salie, Gerard Tromp, Eileen G. Hoal, Craig J. Kinnear, Marlo Möller
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Human Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40246-018-0185-z