In vitro Impact of Yeast Expressed Hybrid Peptide CATH-2TP5 as a Prophylactic Measure Toward Sepsis and Inflammation

In vitro Impact of Yeast Expressed Hybrid Peptide CATH-2TP5 as a Prophylactic Measure Toward Sepsis and Inflammation

CATH-2TP5 is a linear cationic hybrid peptide, consequent from naturally occurring antimicrobial peptide (AMPs) Cathelicidin-2 (CATH-2) and Immunomodulatory peptide Thymopentin (TP5) having dynamic and potent anti-inflammatory activities without hemolytic effect. The biocompatible mechanism of CATH-...

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Bibliographic Details
Main Authors: Baseer Ahmad, Quratulain Hanif, Xubiao Wei, Lulu Zhang, Naveed Sabir, Zhongxuan Li, Junhao Cheng, Shahzad Akbar Khan, Abdul Basit, Muhammad Shahid, Amin ur Rehman, Dayong Si, Rijun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cathelicidin
hybrid peptide
endotoxin neutralization
inflammation
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00454/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00454/full

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