Quantitative Analysis of Antibody Survival across the Infant Digestive Tract Using Mass Spectrometry with Parallel Reaction Monitoring

Orally delivered antibodies may be useful for the prevention of enteric pathogen infection, but to be effective they need to survive intact across digestion through the gastrointestinal tract. As a test case, we fed a recombinant human antibody, palivizumab, spiked into human milk to four infants an...

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Bibliographic Details
Main Authors: Bum Jin Kim, Jiraporn Lueangsakulthai, Baidya Nath P. Sah, Brian Scottoline, David C. Dallas
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/9/6/759