Elevated salivary cortisol predicts response to adjunctive immune modulation in treatment-resistant bipolar depression

Elevated salivary cortisol predicts response to adjunctive immune modulation in treatment-resistant bipolar depression

Background: Adjunctive inflammatory treatments improve response and remission rates in treatment-resistant bipolar depression (TRBDD), but underlying mechanisms remain unclear. Given the association between hypothalamic-pituitary-adrenal (HPA) axis dysregulation and treatment-resistant depression, w...

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Bibliographic Details
Main Authors: Stephen Murata, Michael Murphy, Rajan Khanna, Debra Hoppensteadt, Jawed Fareed, Angelos Halaris
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of Affective Disorders Reports
Subjects:
Bipolar disorder
Treatment-resistant bipolar depression
Hypothalamic-pituitary-adrenal (HPA) axis
Salivary cortisol
Escitalopram
Celecoxib
Online Access:http://www.sciencedirect.com/science/article/pii/S2666915321000445

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http://www.sciencedirect.com/science/article/pii/S2666915321000445

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