Epigenetic regulation of cardiac myocyte differentiation

Epigenetic regulation of cardiac myocyte differentiation

Cardiac myocytes proliferate robustly during fetal life but withdraw permanently from the cell cycle soon after birth and undergo terminal differentiation. This cell cycle exit is associated with upregulation of a host of adult cardiac-specific genes. The vast majority of adult cardiac myocytes do...

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Bibliographic Details
Main Authors: Kyohei eOyama, Danny eEl-Nachef, Yiqiang eZhang, Patima eSdek, William Robb Maclellan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Genetics
Subjects:
Cell Cycle
Retinoblastoma Protein
cardiac myocyte
histone modification
Terminal differentiation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00375/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00375/full

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