Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications of <i>Sleeping Beauty</i>, <i>piggyBac</i> and <i>Tol2</i> for Genome Engineering

Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications of <i>Sleeping Beauty</i>, <i>piggyBac</i> and <i>Tol2</i> for Genome Engineering

Transposons are mobile genetic elements evolved to execute highly efficient integration of their genes into the genomes of their host cells. These natural DNA transfer vehicles have been harnessed as experimental tools for stably introducing a wide variety of foreign DNA sequences, including selecta...

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Bibliographic Details
Main Authors: Nicolás Sandoval-Villegas, Wasifa Nurieva, Maximilian Amberger, Zoltán Ivics
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
transposon
transposition
nonviral
genome engineering
transgenesis
induced pluripotent stem cells
Online Access:https://www.mdpi.com/1422-0067/22/10/5084

Internet

https://www.mdpi.com/1422-0067/22/10/5084

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