Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines.

In previous work, we demonstrated that transcription factor Trim28 (Tripartite motif containing 28) plays a tumor-suppressor role in early-staged adenocarcinoma of the lung due to its ability to restrain transcription of cell cycle-regulating genes. Herein we examine Trim28's role in the epithe...

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Bibliographic Details
Main Authors: Lu Chen, Teresita Muñoz-Antonia, W Douglas Cress
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4077753?pdf=render