Evaluating the Vaccine Potential of a Tetravalent Fusion Protein (rBmHAXT) Vaccine Antigen Against Lymphatic Filariasis in a Mouse Model

Evaluating the Vaccine Potential of a Tetravalent Fusion Protein (rBmHAXT) Vaccine Antigen Against Lymphatic Filariasis in a Mouse Model

Lymphatic filariasis (LF) is a tropical parasitic infection of human transmitted by mosquitoes. Chronic infection results in severe physical disability in the infected patients. Although several potential vaccine antigens were identified by several groups, there are no licensed prophylactic vaccine...

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Bibliographic Details
Main Authors: Nikhil Chauhan, Vishal Khatri, Priyankana Banerjee, Ramaswamy Kalyanasundaram
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
lymphatic filariasis
TLR-4
prophylactic vaccine
aluminum
multivalent antigen
mouse model
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01520/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01520/full

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