Leptin levels in SARS-CoV-2 infection related respiratory failure: A cross-sectional study and a pathophysiological framework on the role of fat tissue

Obesity is a risk factor for SARS-CoV-2 infected patients to develop respiratory failure. Leptin produced in visceral fat might play a role in the deterioration to mechanical ventilation. A cross sectional study was performed. The mean BMI was 31 kg/m2 (range 24.8–48.4) for the 31 SARS-CoV-2 ventila...

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Bibliographic Details
Main Authors: Peter H.J. van der Voort, Jill Moser, Durk F. Zandstra, Anneke C. Muller Kobold, Marjolein Knoester, Cornelis F. Calkhoven, Inge Hamming, Matijs van Meurs
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020315395