Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods

Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods

[<sup>18</sup>F]Fallypride and [<sup>18</sup>F]Fluortriopride (FTP) are two different PET radiotracers that bind with sub-nanomolar affinity to the dopamine D3 receptor (D<sub>3</sub>R). In spite of their similar D<sub>3</sub> affinities, the two PET l...

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Bibliographic Details
Main Authors: Chia-Ju Hsieh, Aladdin Riad, Ji Youn Lee, Kristoffer Sahlholm, Kuiying Xu, Robert R. Luedtke, Robert H. Mach
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
dopamine D3 receptor
[<sup>18</sup>F]Fallypride
[<sup>18</sup>F]Fluortriopride
docking
molecular dynamics
Online Access:https://www.mdpi.com/2218-273X/11/4/529

Internet

https://www.mdpi.com/2218-273X/11/4/529

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