Uropathogenic E. coli Exploit CEA to Promote Colonization of the Urogenital Tract Mucosa.

Attachment to the host mucosa is a key step in bacterial pathogenesis. On the apical surface of epithelial cells, members of the human carcinoembryonic antigen (CEA) family are abundant glycoproteins involved in cell-cell adhesion and modulation of cell signaling. Interestingly, several gram-negativ...

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Bibliographic Details
Main Authors: Petra Muenzner, Arnaud Kengmo Tchoupa, Benedikt Klauser, Thomas Brunner, Johannes Putze, Ulrich Dobrindt, Christof R Hauck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005608