Sirtuin Family Members Selectively Regulate Autophagy in Osteosarcoma and Mesothelioma Cells in Response to Cellular Stress
The class III NAD+ dependent deacetylases-sirtuins (SIRTs) link transcriptional regulation to DNA damage response and reactive oxygen species generation thereby modulating a wide range of cellular signaling pathways. Here, the contribution of SIRT1, SIRT3, and SIRT5 in the regulation of cellular fat...
Main Authors: | Richa Garva, Chutamas Thepmalee, Umpa Yasamut, Sangkab Sudsaward, Alice Guazzelli, Ramkumar Rajendran, Nopprarat Tongmuang, Sasiprapa Khunchai, Parisa Meysami, Thawornchai Limjindaporn, Pa-thai Yenchitsomanus, Luciano Mutti, Marija Krstic-Demonacos, Constantinos Demonacos |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-09-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2019.00949/full |
Similar Items
-
Melatonin Inhibits Dengue Virus Infection via the Sirtuin 1-Mediated Interferon Pathway
by: Atthapan Morchang, et al.
Published: (2021-04-01) -
Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription
by: Ramkumar Rajendran, et al.
Published: (2011-01-01) -
Adaptor Protein 1A Facilitates Dengue Virus Replication.
by: Umpa Yasamut, et al.
Published: (2015-01-01) -
Enhanced cytotoxic activity of effector T-cells against cholangiocarcinoma by dendritic cells pulsed with pooled mRNA
by: Mutita Junking, et al.
Published: (2017-10-01) -
Sirtuins as Important Factors in Pathological States and the Role of Their Molecular Activity Modulators
by: Ewa Maria Kratz, et al.
Published: (2021-01-01)