Role of Macrophages in Cytotoxicity, Reactive Oxygen Species Production and DNA Damage in 1,2-Dichloropropane-Exposed Human Cholangiocytes In Vitro

Role of Macrophages in Cytotoxicity, Reactive Oxygen Species Production and DNA Damage in 1,2-Dichloropropane-Exposed Human Cholangiocytes In Vitro

1,2-Dichloropropane (1,2-DCP), a synthetic chlorinated organic compound, was extensively used in the past in offset color proof-printing. In 2014, the International Agency for Research on Cancer (IARC) reclassified 1,2-DCP from its initial Group 3 to Group 1. Prior to the reclassification, cholangio...

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Bibliographic Details
Main Authors: Abigail Ekuban, Cai Zong, Frederick Adams Ekuban, Yusuke Kimura, Ryoya Takizawa, Kota Morikawa, Kazuo Kinoshita, Sahoko Ichihara, Seiichiroh Ohsako, Gaku Ichihara
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Toxics
Subjects:
1,2-Dichloropropane
cytotoxicity
cholangiocarcinoma
chemical carcinogenesis
work safety
carcinogenic compounds
Online Access:https://www.mdpi.com/2305-6304/9/6/128

Internet

https://www.mdpi.com/2305-6304/9/6/128

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