Noscapine Prevents Rotenone-Induced Neurotoxicity: Involvement of Oxidative Stress, Neuroinflammation and Autophagy Pathways

Noscapine Prevents Rotenone-Induced Neurotoxicity: Involvement of Oxidative Stress, Neuroinflammation and Autophagy Pathways

Parkinson’s disease is characterized by the loss of dopaminergic neurons in substantia nigra pars compacta (SNpc) and the resultant loss of dopamine in the striatum. Various studies have shown that oxidative stress and neuroinflammation plays a major role in PD progression. In addition, the autophag...

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Bibliographic Details
Main Authors: Richard L. Jayaraj, Rami Beiram, Sheikh Azimullah, Nagoor Meeran M. F., Shreesh K. Ojha, Abdu Adem, Fakhreya Yousuf Jalal
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
Parkinson’s disease
noscapine
rotenone
oxidative stress
inflammation
autophagy
Online Access:https://www.mdpi.com/1420-3049/26/15/4627

Internet

https://www.mdpi.com/1420-3049/26/15/4627

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