Rapamycin and mTOR: a serendipitous discovery and implications for breast cancer
Abstract Rapamycin was discovered more than thirty years ago from a soil sample from the island of Rapa Nui. It was isolated from Streptomyces hygroscopicus and initial characterization focused on its antifungal activities. Subsequent characterization showed that it has immunosuppressive properties...
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Format: | Article |
Language: | English |
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Wiley
2012-12-01
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Series: | Clinical and Translational Medicine |
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Online Access: | https://doi.org/10.1186/2001-1326-1-29 |