Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice

Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice

<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and non-steroidal anti-inflammatories diminish the risk of suffering the neurologic disease. Cannabinoids are neuroprotective and anti-inflammatory agents wi...

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Bibliographic Details
Main Authors: Martín-Moreno Ana María, Brera Begoña, Spuch Carlos, Carro Eva, García-García Luis, Delgado Mercedes, Pozo Miguel A, Innamorato Nadia G, Cuadrado Antonio, de Ceballos María L
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Journal of Neuroinflammation
Subjects:
Alzheimer's disease
β-amyloid peptide
cannabinoids
glial activation
interleukin 6
anti-inflammatories
tumor necrosis factor-α
Online Access:http://www.jneuroinflammation.com/content/9/1/8

Internet

http://www.jneuroinflammation.com/content/9/1/8

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