ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells

Reactive oxygen species (ROS) are by-products of normal cell activity. They are produced in many cellular compartments and play a major role in signaling pathways. Overproduction of ROS is associated with the development of various human diseases (including cancer, cardiovascular, neurodegenerative,...

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Main Authors: Anastasiya V. Snezhkina, Anna V. Kudryavtseva, Olga L. Kardymon, Maria V. Savvateeva, Nataliya V. Melnikova, George S. Krasnov, Alexey A. Dmitriev
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/6175804