A novel merozoite surface antigen of Plasmodium falciparum (MSP-3) identified by cellular-antibody cooperative mechanism antigenicity and biological activity of antibodies

We report the identification of a 48kDa antigen targeted by antibodies which inhibit Plasmodium falciparum in vitro growth by cooperation with blood monocytes in an ADCI assay correlated to the naturally acquired protection. This protein is located on the surface of the merozoite stage of P. falcipa...

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Bibliographic Details
Main Authors: Claude Oeuvray, Hasnaa Bouharoun-Tayoun, Heléne Grass-Masse, Jean Paul Iepers, Laurence Ralamboranto, André Tartar, Pierre Druilhe
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1994-01-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000600018