Sytemic inflammation in cachexia - is tumour cytokine expression profile the culprit?

Sytemic inflammation in cachexia - is tumour cytokine expression profile the culprit?

Cachexia affects about 80 percent of gastrointestinal cancer patients. This multifactorial syndrome resulting in involuntary and continuous weight loss is accompanied by systemic inflammation and immune cell infiltration in various tissues. Understanding the interactions between tumor, immune cells...

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Bibliographic Details
Main Authors: Emidio Marques De Matos-Neto, Joanna Darck Carola Correia Lima, Welbert de Oliveira Pereira, Raquel Galvão Figuerêdo, Daniela Mendes dos Reis Riccardi, Katrin eRadloff, Rodrigo Xavier das Neves, Rodolfo Gonzalez Camargo, Linda Ferreira Maximiano, Flávio eTokeshi, José Pinhata Otoch, Niels Olsen Saraiva Camara, Romina eGoldszmid, Giorgio eTrinchieri, Paulo Sérgio Martins de Alcantara, Marilia eSeelaender
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
Cytokines
Cancer cachexia
macrophages.
inflammatory cells
tumor-adipose tissue crosstalk
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00629/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00629/full

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