Effects of Angiotensin Type I Receptor Blockade on the Cardiac Raf/MEK/ERK Cascade Activated via Adrenergic Receptors

Effects of Angiotensin Type I Receptor Blockade on the Cardiac Raf/MEK/ERK Cascade Activated via Adrenergic Receptors

A close interaction between adrenergic nerves and angiotensin systems has been documented. The present study was designed to investigate the mechanisms of angiotensin-receptor blocker (ARB) suppression of β-adrenergic receptor stimulation–induced cardiac hypertrophy. Chronic isoproterenol (ISO)–indu...

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Bibliographic Details
Main Authors: Guo-Xing Zhang, Shoji Kimura, Koji Murao, Xiao Yu, Koji Obata, Hiroko Matsuyoshi, Miyako Takaki
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319309168

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http://www.sciencedirect.com/science/article/pii/S1347861319309168

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