Synthesis and Preliminary Antimicrobial Activities of New Arylideneamino-1,3,4-thiadiazole-(thio/dithio)-acetamido Cephalosporanic Acids
New derivatives of 7-aminocephalosporanic acid 1–8 were synthesized by acylation of the 7-amino group of the cephem nucleus with various arylidinimino-1,3,4-thiadiazole-thio(or dithio)-acetic acid intermediates 3a–d and 5a–d, respectively, so the acyl side chains of these new cephalosporins containe...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/1/1025/ |